Weight Regain after
Gastric Bypass:
Endoscopic Treatment
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Weight Regain after Gastric Bypass
Weight Regain after Gastric Bypass
Author: Dr Waqas Fazal, Interventional and Bariatric Gastroenterologist
Published on: [07/09/25]
Gastric bypass is one of the most effective tools we have for long-term weight loss. Most people lose a large amount of weight in the first 1–2 years, often improving or even reversing conditions like diabetes, high blood pressure, and sleep apnea.
It is important to know though that significant weight regain after surgery is common.
What is considered 'Weight Regain'?
What is considered 'Weight Regain'?
Doctors usually define it as gaining back at least 25% of the weight you lost after surgery. Some regain is expected — your body naturally tries to fight weight loss — but for some people, it can be more than they hoped.
How Common Is It?
How Common Is It?
It is quite common for people to start gaining weight 2 years after the surgery. A large study on this topic found that ‘excessive weight regain’, defined as ≥25 % of total lost weight, occurs in 37 % of patients. [1]
Even so, most people still weigh much less than before their surgery and keep many of the health benefits.
Gastric Bypass Anatomy
TORe (Transoral Outlet Reduction Endoscopy)
Why Does Weight Regain Happen?
Why Does Weight Regain Happen?
There’s no single reason and usually a mix of factors:
Anatomical changes:
It has been found that dilation of the stomach outlet (surgical joint between gastric pouch and small bowel) over time, can lead to increased food intake and weight regain. This prevents food from staying in the stomach for longer, making you hungrier sooner.
Similarly the gastric pouch (remnant stomach) can stretch over time, allowing more food to be consumed in one time.Eating habits creeping back in: Snacking (“grazing”), high-calorie food intake
Decreased physical activity
Emotional eating
Metabolism adjusting: Your body becomes more efficient and burns fewer calories, which is a natural survival response.
What Can Be Done About It?
What Can Be Done About It?
Behavioral support and nutritional guidance are of utmost importance in managing unhelpful eating patterns and building healthier habits. Once these services have been engaged further support may be needed
1. Medications
New weight-loss medications, like GLP-1 medications (Wegovy and Mounjaro), can help people who have regained weight after surgery.
These work best when combined with healthy eating and lifestyle changes.
2. Endoscopic Procedures
In search of non-surgical ways of managing weight regain after gastric bypass, some pretty clever endoscopic techniques have been developed. These are less invasive and safer than revisional bariatric surgery.
A treatment called TORe (Transoral Outlet Reduction Endoscopy) is one such very successful technique. This is an endoscopic procedure, where an endoscope is passed through the mouth to suture and tighten the stomach outlet if it has stretched.
If the gastric pouch has dilated overtime, this can tightened/sutured at the same time too.
This is less invasive and safer than surgery and can help patients lose weight again. Studies have shown a total body weight loss of around 10 % with TORe at 12 months. [2]
5. Revisional Surgery
In some cases, a second operation may be needed — for example, to resize the pouch or adjust the bypass.
This option is usually considered only if other treatments haven’t worked, as it carries more risk than the first surgery.
Cooper TC, Simmons EB, Webb K, Burns JL, Kushner RF. Trends in Weight Regain Following Roux-en-Y Gastric Bypass (RYGB) Bariatric Surgery. Obes Surg. 2015 Aug;25(8):1474-81. doi: 10.1007/s11695-014-1560-z. PMID: 25595383.
Pontecorvi V, Matteo MV, Bove V, De Siena M et al. Long-term Outcomes of Transoral Outlet Reduction (TORe) for Dumping Syndrome and Weight Regain After Roux-en-Y Gastric Bypass. Obes Surg. 2023 Apr;33(4):1032-1039. doi: 10.1007/s11695-023-06466-w. Epub 2023 Jan 27. PMID: 36702981; PMCID: PMC10079715.
Ready to Take the Next Step?
Ready to Take the Next Step?
If you have regained weight after gastric bypass and want to explore non-surgical weight loss options, book a consultation with Dr Fazal.
📞 Call us at [07 35222900]
📧 Email: [admin@gastroscope.clinic]
💻 Book online at [Request Appointment ]
Disclaimer: This article is for educational purposes only and is not a substitute for medical advice. Always consult a qualified healthcare provider.
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